Anti-ERBB4 Polyclonal Antibody-抗体-抗体-生物在线
Anti-ERBB4 Polyclonal Antibody

Anti-ERBB4 Polyclonal Antibody

商家询价

产品名称: Anti-ERBB4 Polyclonal Antibody

英文名称: ALS19;HER4;p180erbB4

产品编号: K001747P

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: null

使用范围: WB

北京索莱宝科技有限公司--实验室产品
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This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.