Anti-MAP3K10抗体-抗体-抗体-生物在线
Anti-MAP3K10抗体

Anti-MAP3K10抗体

商家询价

产品名称: Anti-MAP3K10抗体

英文名称: MAP3K10

产品编号: YB--6781R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-MAP3K10抗体

产品编号 YB-6781R
英文名称 MAP3K10
中文名称 丝裂原活化蛋白激酶3K10抗体
别    名 Activates the JUN N-terminal pathway; M3K10_HUMAN.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  信号转导  细胞凋亡  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, Xenopuslaevis
产品应用 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 104kDa
细胞定位 细胞浆 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MLK2/MAP3K10:421-480/954 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008].

Function:
Activates the JUN N-terminal pathway (By similarity). 

Subunit:
Homodimer (By similarity). 

Tissue Specificity:
Expressed in brain and skeletal muscle.

Post-translational modifications:
Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation (By similarity).

Similarity:
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. 
Contains 1 protein kinase domain. 
Contains 1 SH3 domain. 

SWISS:
Q02779

Gene ID:
4294

Database links:

Entrez Gene: 4294 Human

Entrez Gene: 269881 Mouse

Entrez Gene: 308463 Rat

Omim: 600137 Human

SwissProt: Q02779 Human

SwissProt: Q66L42 Mouse

Unigene: 466743 Human

Unigene: 389883 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application