中文名称 磷酸化丝裂原活化蛋白激酶激酶1/2重组兔单克隆抗体 
别    名 MEK1(S218/S222); MEK1 + MEK2 (phospho S218 + S222); p-MEK1 + MEK2 (phospho S218 + S222); MAP2K1(phospho S218/S222); Dual specificity mitogen activated protein kinase kinase 1; ERK activator kinase 1; MAP kinase kinase 1; MAP kinase/Erk kinase 1; MAP/Erk kinase 1; Map2K1; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; MEKK1; Mitogen activated protein kinase kinase 1; MKK 1; MKK1; PRKMK 1; PRKMK1;Protein kinase mitogen activated kinase 1 (MAP kinase kinase 1); Protein kinase mitogen activated kinase 1; Protein kinase mitogen activated, kinase 1.    
产品类型 磷酸化抗体  
研究领域 肿瘤  免疫学  神经生物学  信号转导  细胞凋亡  转录调节因子  激酶和磷酸酶   
抗体来源 Rabbit 
克隆类型 Monoclonal 
克 隆 号 8A1 
交叉反应 Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Rabbit, ) 
产品应用 WB=1:500-2000 IP=1:20-100 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. 
分 子 量 43kDa 
细胞定位 细胞核 细胞浆 细胞膜  
性    状 Liquid 
浓    度 1mg/ml 
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human MEK1 around the phosphorylation site of Ser218/222:ID(p-S)MAN(p-S)FV  
亚    型 IgG 
纯化方法 affinity purified by Protein A 
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 
PubMed PubMed 
产品介绍 The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and developme